a tool for identifying drug-targetable redox-active disulphides

Spermadhesin-1

Intramolecular

Cysteine 30 and cysteine 51

A redox-regulated disulphide may form within Spermadhesin-1 between cysteines 30 and 51 (10 and 31 respectively in this structure).

Details

Redox score ?

84

PDB code

Structure name

crystal structure of acidic seminal fluid protein (asfp) at 1

Structure deposition date

1997-06-24

Thiol separation (Å)

2

Half-sphere exposure sum ?

56

Minimum pK_a ?

nan

% buried

nan

Peptide accession

Residue number A

30

Residue number B

51

Peptide name

Spermadhesin-1

Ligandability

Cysteine 30 of Spermadhesin-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

Cysteine 51 of Spermadhesin-1

Not ligandable in the dataset of Yang et al.

Not ligandable in the dataset of Yan et al.

Not ligandable in the dataset of Backus et al.

Not ligandable in the dataset of Vinogradova et al.

Not ligandable in the dataset of Cao et al.

Not ligandable in the dataset of Kuljanin et al.

If this tool was useful for finding a disulphide, please cite: